Ischemic preconditioning in hepatic ischemic–reperfusion injury
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چکیده
منابع مشابه
Ischemic preconditioning in hepatic ischemic-reperfusion injury
http://dx.doi.org/10.1016/j.fjs.2016. 1682-606X/Copyright a 2016, Taiwan S NC-ND license (http://creativecommo Abstract Background/Introduction: Ischemic preconditioning is a method in which brief periods of ischemia render tissues resistant to injury resulting from prolonged ischemia and reperfusion, so-called ischemiaereperfusion injury. Purpose: To elucidate the possible protective role of i...
متن کاملRole of ischemic preconditioning in hepatic ischemia-reperfusion injury.
BACKGROUND Investigation into less traumatic method of vascular occlusion during liver resection is the actual problem in hepatic surgery because of high level of complications such as liver failure. In this connection, the goal of our study was to determine the optimal model of vascular clamping. The research showed that vascular occlusion with ischemic preconditioning in the mode 5/10/15 the ...
متن کاملThe Effects of Remote Ischemic Preconditioning and N-Acetylcysteine with Remote Ischemic Preconditioning in Rat Hepatic Ischemia Reperfusion Injury Model
BACKGROUND Remote ischemic preconditioning (RIP) and pharmacological preconditioning are the effective methods that can be used to prevent ischemia reperfusion (IR) injury. The aim of this study was to evaluate the effects of RIP and N-Acetylcysteine (NAC) with RIP in the rat hepatic IR injury model. MATERIALS AND METHODS 28 rats were divided into 4 groups. Group I (sham): only laparotomy was...
متن کامل[Molecular mechanisms in liver ischemic-reperfusion injury and ischemic preconditioning].
Ischemia-reperfusion (IR) liver injury is associated with temporary clamping of hepatoduodenal ligament during liver surgery, hypoperfusion shock and graft failure after liver transplantation. Mechanisms of IR liver injury include: i) loss of calcium homeostasis, ii) reactive oxygen and nitrogen species generation, iii) changes in microcirculation, iv) Kupffer cell activation, and (v) complemen...
متن کاملReduction of hemorrhagic shock–induced acute kidney injury by lower limb ischemic preconditioning in rats
Introduction: During hemorrhagic shock (HS), the kidneys are one of the primary target organs involved. Oxidative stress is shown to be enhanced in different models of acute kidney injury (AKI). Remote ischemic preconditioning (RPC) by brief limb ischemia is considered to be a safe method to protect different organs from further damage. In this study, we investigated the effects of brief hind l...
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ژورنال
عنوان ژورنال: Formosan Journal of Surgery
سال: 2016
ISSN: 1682-606X
DOI: 10.1016/j.fjs.2016.03.003